The Jalili Lab

The interplay between the commensal microbiota and the mammalian immune system development and function includes multifold interactions in homeostasis and disease. The Jalili Research Group at The Jackson Laboratory (JAX) is focused on interrogating the host immunity, microbiome and their interface in the context of infectious diseases, autoimmunity and cancer. Our laboratory uses different engineering tools, such as microneedle skin patches, organoid engineering and organ on chip systems to not only unravel the microbiome-immune crosstalk but also develop novel therapeutic modalities for immune-related diseases.